UCR

Environmental Toxicology



Pengcheng Wang


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UCR Phone:
Email: pengcheng.wang@email.ucr.edu
UCR Major Professor: Yinsheng Wang
Degree Program: PhD

Pengcheng Wang

B.S. Pharmacy, Wuhan University / M.S. Wuhan University

Research Focus

Replicative bypass and mutagenic properties of alkylated nucleosides

Publications

  • Wang P, Amato NJ, Zhai Q and Wang Y, Cytotoxic and mutagenic properties of O4-alkylthymidine lesions in Escherichia coli cells. Nucleic Acids Res., 2015, in press;
  • Fu L, Amato NJ, Wang P, McGowan SJ, Niedernhofer LJ, Wang Y, Simultaneous Quantification of Methylated Cytidine and Adenosine in Cellular and Tissue RNA by Nano-Flow Liquid Chromatography-Tandem Mass Spectrometry Coupled with the Stable Isotope-Dilution Method. Anal Chem., 2015, 87(15):7653-7659;
  • You C, Wang P, Dai X, Wang Y, Transcriptional bypass of regioisomeric ethylated thymidine lesions by T7 RNA polymerase and human RNA polymerase II. Nucleic Acids Res., 2014, 42(22): 13706-13713;
  • Zhang F, Paramasivam M, Cai Q, Dai X, Wang P, Lin K, Song J, Seidman MM and Wang Y, Arsenite Binds to the RING Finger Domains of RNF20-RNF40 Histone E3 Ubiquitin Ligase and Inhibits DNA Double-strand Break Repair, J. Am. Chem. Soc., 2014, 136(37):12884-12887;
  • Zhai Q, Wang P, Cai Q and Wang Y, Syntheses and Characterizations of the in-vivo Cytotoxic and Mutagenic Properties of the Minor-groove O2-Alkylthymidine Lesions, Nucleic Acids Res., 2014, 42(16):10529-10537;
  • Ji D, You C, Wang P and Wang Y, Effects of Tet-induced Oxidation Products of 5-Methylcytosine on DNA Replication in Mammalian Cells, Chem. Res. Toxicol., 2014, 27(7):1304-1309;
  • Zhai Q*, Wang P* and Wang Y, Cytotoxic and Mutagenic Properties of Regioisomeric O2-, N3- and O4-Ethylthymidines in Bacterial Cells, Carcinogenesis, 2014, 35(9):2002-2006;
  • Wang P, Williams RT, Guerrero CR, Ji D and Wang Y, Fragmentation of electrospray-produced deprotonated ions of oligodeoxyribonucleotides containing an alkylated or oxidized thymidine, J. Am. Soc. Mass Spectrom., 2014, 25(7): 1167-1176;
  • Andersen N*, Wang P* and Wang Y, Replication across Regioisomeric Ethylated Thymidine Lesions by Purified DNA Polymerases, Chem. Res. Toxicol., 2013, 26(11): 1730-1738;
  • Andersen N, Wang J, Wang P, Jiang Y, and Wang Y, In-Vitro Replication Studies on O2-Methylthymidine and O4-Methylthymidine. Chem. Res. Toxicol., 2012, 25(11):2523-2531.

Presentations

  • Wang P, Amato NJ, Zhai Q and Wang Y*, Replicative bypass and mutagenic properties of O4-alkylthymidine lesions in E. coli , Oral presentation, Young Investigator Symposium, 250th American Chemical Society National Meeting, Boston, MA, 2015.
  • Wang P, Zhai Q and Wang Y*, In vivo Replication Studies of O2-alkyl Thymidine Adducts, Oral presentation, Young Investigator Symposium, 248th American Chemical Society National Meeting, San Francisco, CA, 2014.
  • Zhai Q, Wang P and Wang Y*, In vivo Replication Studies of Ethylated Thymidine Adducts, Poster, 246th American Chemical Society National Meeting, Indianapolis, IN, 2013.

More Information

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Environmental Toxicology Graduate Program
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