UCR

Environmental Toxicology



Nicole Williams


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UCR Phone:
Email: nicole.williams001@email.ucr.edu
UCR Major Professor: Yinsheng Wang
Degree Program: Ph.D.

Nicole Williams

Cal Baptist University, M.S., Kinesiology; University of Colorado, Colorado Springs, B.S., Health Care Science

Research Focus

My work focuses on investigating the effects of various types of alkylated and oxidized DNA lesions on DNA replication and transcription.

Publications

  • Williams, N. L., Amato, N. J., and Wang, Y. (2017). Replicative bypass studies of a-anomeric lesions of 2-deoxyribonucleosides in vitro. Chem. Res. Toxicol. Accepted
  • Williams, N. L., Wang, P., and Wang, Y. (2016). Replicative bypass of O2-alkylthymidine lesions in vitro. Chem. Res. Toxicol., 29(10): 1755-1761
  • Wu, J., Li, L., Wang, P., You, C., Williams, N. L., and Wang, Y. (2016). Translesions synthesis of O4-alkylthymidine lesions in human cells. Nucleic Acids Res., 44(19): 9256-9256
  • Williams, N. L., Wang, P., Wu, J., and Wang, Y. (2016). In vitro lesion bypass studies of O4-alkythymidines with human polymerase eta. Chem. Res. Toxicol., 29(4): 669-675
  • Williams, N., Coburn, J., and Gillum, T. (2015). Static stretching vs. dynamic warm-ups: a comparison of their effects on torque and electromyography output of the quadriceps and hamstring muscles. J. Sports Med. and Phys. Fitness, 55(11): 1310-1317
  • Gillum, T., Keunnen, M., Castillo, M., Williams, N., Jordan-Patterson, A. (2015). Exercise, but not acute sleep loss, increases salivary antimicrobial protein secretion. J. Strength Cond. Res., 29(5): 1359-1366

 

Presentations

  • ACS 250th National Meeting & Exposition, August 2015, In vitro replication studies of O2- and O4-alkylthymidine lesions with human DNA polymerase η. Nicole Williams, Pengcheng Wang, Jiabin Wu and Yinsheng Wang; Oral presentation.

     

  • UC Riverside Environmental Toxicology Annual Research Symposium, 19 June 2015, In vitro replication studies of O2- and O4-alkylthymidine lesions with human DNA polymerase η. Nicole Williams, Pengcheng Wang, Jiabin Wu and Yinsheng Wang; Oral presentation.

     

  • UC Riverside Environmental Toxicology Annual Research Symposium, 20 June 2014, In vitro Replication Studies of the Tet-Mediated Products of 5-Methylcytosine by Mitochondrial DNA Polymerase γ. Nicole Williams, Pengcheng Wang and Yinsheng Wang; Oral presentation.

 

  • Mammalian DNA Repair Gordon Research Conference, February 2017, Repair and transcriptional mutagenesis of minor-groove O2- alkylated thymidine lesions. Nicole Williams, Changjun You, Pengcheng Wang, and Yinsheng Wang; Poster Presentation.

 

  • SoCal Genome Stability Symposium, December 2016. Repair and transcriptional mutagenesis of minor-groove O2- alkylated thymidine lesions. Nicole Williams, Changjun You, Pengcheng Wang, and Yinsheng Wang; Oral Presentation.

 

  • ACS 252nd National Meeting and Exposition, August 2016. Transcriptional Bypass of O2- alkylthymidine Lesions by T7 RNA Polymerase and Human RNA Polymerase II. Nicole Williams, Pengcheng Wang and Yinsheng Wang; Oral presentation.

 

  • DNA Damage, Mutation & Cancer Gordon Research Conference, March 2016, The roles of DNA polymerases eta, iota, kappa and zeta in the bypass of O2- and O4-alkylthymide lesions in vitro and in human cells. Nicole Williams, Jun Wu and Yinsheng Wang; Poster presentation.

More Information

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

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Department Information

Environmental Toxicology Graduate Program
1140 Batchelor Hall

Tel: (951) 827-4116
Alt Tel: (800) 735-0717
E-mail: BSGSAC Graduate Student Advisor - etox@ucr.edu

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